Figure 2.
Under the polygenic multiplicative model, for a disease with average lifetime risk
of 5%, the distribution of lifetime risk for: (a) the population; and for people at
increased familial risk profile by on average (b) 2-fold; (c) 4-fold; and (c) 8-fold.
Hopper Epidemiologic Perspectives & Innovations 2011 8:2 doi:10.1186/1742-5573-8-2 |