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Scenario for Example 1 |
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| Variables and parameters characterizing the set-up |
Values of parameters and variables |
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| Stratification/Proxy Z (with J strata) |
Past work in metal industry |
| No: Z = 1 |
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| Yes: Z = 2 |
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| Phase One prevalence among controls (τ0j) |
Z = 1: τ01 = 80% |
| Z = 2: τ02 = 20%* |
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| Risk factor X (with K outcomes) |
Exposure to MWF |
| No: X = 1 |
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| Yes: X = 2 |
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| Disease Model (Odds Ratios) (ψk) |
ψ1 = 1: baseline risk |
| ψ2 = 2# |
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| Phase Two prevalence of X among controls by stratum (π0jk) |
Z = 1: π011 = 97.5%, π012 = 2.5%& Z = 2: π021 = 75%, π022 = 25%@ |
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*20% prevalence of having worked in the metal industry #Exposure to MWF doubles the risk of bladder cancer &Among non-metal-industry workers, 2.5% exposed to MWF @Among metal-industry workers, 25% exposed to MWF | |
Wild et al. Epidemiologic Perspectives & Innovations 2008 5:4 doi:10.1186/1742-5573-5-4 |
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