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Open AccessAnalytic Perspective

Flexible Two-Phase studies for rare exposures: Feasibility, planning and efficiency issues of a new variant

Pascal Wild1 email, Nadine Andrieu2,3,4 email, Alisa M Goldstein5 email and Walter Schill6 email

INRS, French National Institute for Research and Safety, Department of Epidemiology, France

INSERM, U900, Paris, F-75248, France

Institut Curie, Paris, F-75248, France

Ecole des Mines de Paris, ParisTech, Fontainebleau, F-77300, France

Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, USA

BIPS, Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Germany

author email corresponding author email

Epidemiologic Perspectives & Innovations 2008, 5:4doi:10.1186/1742-5573-5-4

Published: 1 October 2008

Additional files

Additional file 1:

This is a text file containing the code of the Stata statistical software (StataCorp. 2007; Stata Statistical Software: Release 9 and onwards. College Station, TX: StataCorp LP.) for fitting two-phase data. It can be accessed using any text processor but can only be executed within Stata. It should be saved under the name blogit_2P.ado.

Format: TXT Size: 10KB Download file

Additional file 2:

This is a help file describing the preceding program and its options. In can only be displayed as a help file from within Stata. It should be saved under the name blogit_2P.hlp.

Format: TXT Size: 3KB Download file

Additional file 3:

This is a text file containing the code of the Stata statistical software for performing the power computation for Example 1 using the above program and performing the computations shown in figure 1. In reads in the data in the data file MWF.raw included as Additional file 4. It can be accessed using any text processor but can only be executed within Stata. It should be saved under the name figure1.do.

Format: TXT Size: 1KB Download file

Additional file 4:

This is text file containing the data obtained by performing the computations shown in Appendix 2. It is used by the Stata program figure1.do included as Additional file 3. It should be saved under the name mwf.raw.

Format: TXT Size: 1KB Download file


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